Buffer overflow in Htslib

CVE-2026-31969

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. When reading data encoded using the `BYTE_ARRAY_STOP` method, an out-by-one error in the `cram_byte_array_stop_decode_char()` function check for a full output buffer could result in a single attacker-controlled byte being written beyond the end of a heap allocation. Exploiting this bug causes a heap buffer overflow. If a user opens a file crafted to exploit this issue, it could lead to the program crashing, or overwriting of data and heap structures in ways not expected by the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Vulnerability class: Buffer Overflow

EPSS: 0.003 (26.1th percentile) — read the EPSS interpretation.

CVSS v3 metric

CVSS v3 base score 8.1 (High). Vector: CVSS:3.1/AV:N/AC:L/PR:N/UI:R/S:U/C:N/I:H/A:H.

Affected products

Weakness classification (CWE)

References

Frequently asked questions

What is CVE-2026-31969?
CVE-2026-31969 is a high-severity vulnerability in Htslib, classified under Heap-based Buffer Overflow. CVSS score: 8.1/10. Published 2026-03-18.
How severe is CVE-2026-31969?
High severity. CVSS v3 base score is 8.1 out of 10.