Buffer overflow in Htslib

CVE-2026-31968

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. For the `VARINT` and `CONST` encodings, incomplete validation of the context in which the encodings were used could result in up to eight bytes being written beyond the end of a heap allocation, or up to eight bytes being written to the location of a one byte variable on the stack, possibly causing the values to adjacent variables to change unexpectedly. Depending on the data stream this could result either in a heap buffer overflow or a stack overflow. If a user opens a file crafted to exploit this issue it could lead to the program crashing, overwriting of data structures on the heap or stack in ways not expected by the program, or changing the control flow of the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Vulnerability class: Buffer Overflow

Published · last modified .

CVSS v3 metric

CVSS v3 base score 8.1 (High). Vector: CVSS:3.1/AV:N/AC:L/PR:N/UI:R/S:U/C:N/I:H/A:H.

EPSS exploit prediction

EPSS: 0.005 (41.8th percentile), scored .

Very low probability of exploitation in the next 30 days; routine patching cadence is appropriate. 42nd percentile — 41.8% of CVEs in the catalogue have a lower EPSS than this one. How to read EPSS.

EPSS trend (30 days)EPSS over the last 30 days for CVE-2026-31968: held from 0.004 to 0.005.

EPSS over last 30 days · oldest: 0.004 · newest: 0.005 · change: +0.001

Affected products

Weakness classification (CWE)

References

Frequently asked questions

What is CVE-2026-31968?
CVE-2026-31968 is a high-severity vulnerability in Htslib, classified under Stack-based Buffer Overflow. CVSS score: 8.1/10. Published 2026-03-18.
How severe is CVE-2026-31968?
High severity. CVSS v3 base score is 8.1 out of 10.