Deserialization in Project-Monai Monai

CVE-2026-100846

MONAI before 1.5.2 contains a deserialization of untrusted data vulnerability in the algo_from_pickle function in monai/auto3dseg/utils.py. The function reads a .pkl file and passes its contents to pickle.loads without validating the data source or content. If an application invokes algo_from_pickle on an attacker-supplied pickle file, an object defining __reduce__ is executed during deserialization, resulting in arbitrary code execution in the context of the application.

Vulnerability class: Insecure Deserialization

Published · last modified .

CVSS v3 metric

CVSS v3 base score 7.6 (High). Vector: CVSS:3.1/AV:N/AC:H/PR:H/UI:R/S:C/C:H/I:H/A:H.

EPSS exploit prediction

EPSS: 0.004 (30.2th percentile), scored .

Very low probability of exploitation in the next 30 days; routine patching cadence is appropriate. 30th percentile — 30.2% of CVEs in the catalogue have a lower EPSS than this one. How to read EPSS.

EPSS trend (30 days)EPSS over the last 30 days for CVE-2026-100846: held from 0.003 to 0.004.

EPSS over last 30 days · oldest: 0.003 · newest: 0.004 · change: +0.001

Affected products

Weakness classification (CWE)

References

Frequently asked questions

What is CVE-2026-100846?
CVE-2026-100846 is a high-severity vulnerability in Project-Monai Monai, classified under Deserialization of Untrusted Data. CVSS score: 7.6/10. Published 2026-09-27.
How severe is CVE-2026-100846?
High severity. CVSS v3 base score is 7.6 out of 10.