Deserialization in Project-Monai Monai

CVE-2026-100845

MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline.

Vulnerability class: Insecure Deserialization

Published .

CVSS v3 metric

CVSS v3 base score 7.8 (High). Vector: CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H.

EPSS exploit prediction

No EPSS score from FIRST.org yet. New CVEs usually get one within a few days; no score means no signal yet, not low risk. How EPSS works.

Affected products

Weakness classification (CWE)

References

Frequently asked questions

What is CVE-2026-100845?
CVE-2026-100845 is a high-severity vulnerability in Project-Monai Monai, classified under Deserialization of Untrusted Data. CVSS score: 7.8/10. Published 2026-09-27.
How severe is CVE-2026-100845?
High severity. CVSS v3 base score is 7.8 out of 10.