What is CVE-2026-100843?

CVE-2026-100843 is a high-severity vulnerability in Project-Monai Monai, classified under Deserialization of Untrusted Data. CVSS score: 7.8/10. Published 2026-09-27.

How severe is CVE-2026-100843?

High severity. CVSS v3 base score is 7.8 out of 10.

Deserialization in Project-Monai Monai

CVE-2026-100843

MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to unsafe pickle.loads() deserialization in monai/auto3dseg/utils.py. Attackers can craft malicious pickle files that execute arbitrary system commands when deserialized by the vulnerable function.

Vulnerability class: Insecure Deserialization

Published 2026-09-27.

CVSS v3 metric

CVSS v3 base score 7.8 (High). Vector: CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H.

EPSS exploit prediction

No EPSS score from FIRST.org yet. New CVEs usually get one within a few days; no score means no signal yet, not low risk. How EPSS works.

Affected products

Project-Monai Monai

Weakness classification (CWE)

CWE-502 — Deserialization of Untrusted Data

References

github.com/Project-MONAI/MONAI/security/advisories/GHSA-qxq5-qhx6-94qw (vendor-advisory)
www.vulncheck.com/advisories/monai-before-1.6.0-remote-code-execution-via-algo-… (third-party-advisory)

Frequently asked questions

What is CVE-2026-100843?: CVE-2026-100843 is a high-severity vulnerability in Project-Monai Monai, classified under Deserialization of Untrusted Data. CVSS score: 7.8/10. Published 2026-09-27.
How severe is CVE-2026-100843?: High severity. CVSS v3 base score is 7.8 out of 10.