What is CVE-2025-27580?

CVE-2025-27580 is a high-severity vulnerability in Nih Brics, classified under Incorrect Usage of Seeds in Pseudo-Random Number Generator (PRNG). CVSS score: 7.5/10. Published 2025-04-24.

How severe is CVE-2025-27580?

High severity. CVSS v3 base score is 7.5 out of 10.

Is CVE-2025-27580 known to be exploited?

4 public proof-of-concept repositories are indexed. Not currently listed in the CISA KEV catalog.

Vulnerability in Nih Brics

CVE-2025-27580

NIH BRICS (aka Biomedical Research Informatics Computing System) through 14.0.0-67 generates predictable tokens (that depend on username, time, and the fixed 7Dl9#dj- string) and thus allows unauthenticated users with a Common Access Card (CAC) to escalate privileges and compromise any account, including administrators.

Published 2025-04-24 · last modified 2026-06-17.

CVSS v3 metric

CVSS v3 base score 7.5 (High). Vector: CVSS:3.1/AV:N/AC:H/PR:L/UI:N/S:U/C:H/I:H/A:H.

EPSS exploit prediction

EPSS: 0.007 (52.6th percentile), scored 2026-10-19.

Very low probability of exploitation in the next 30 days; routine patching cadence is appropriate. 53rd percentile — 52.6% of CVEs in the catalogue have a lower EPSS than this one. How to read EPSS.

EPSS over last 30 days · oldest: 0.007 · newest: 0.007 · change: 0.000

Affected products

Nih Brics — versions 0

Weakness classification (CWE)

CWE-335 — Incorrect Usage of Seeds in Pseudo-Random Number Generator (PRNG)

Public proof-of-concept exploits

References

Frequently asked questions

What is CVE-2025-27580?: CVE-2025-27580 is a high-severity vulnerability in Nih Brics, classified under Incorrect Usage of Seeds in Pseudo-Random Number Generator (PRNG). CVSS score: 7.5/10. Published 2025-04-24.
How severe is CVE-2025-27580?: High severity. CVSS v3 base score is 7.5 out of 10.
Is CVE-2025-27580 known to be exploited?: 4 public proof-of-concept repositories are indexed. Not currently listed in the CISA KEV catalog.