XPath Injection in Openclinica Community Edition
CVE-2025-12921
A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.
Published · last modified .
CVSS v3 metric
CVSS v3 base score 4.3 (Medium). Vector: CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:L/I:N/A:N.
EPSS exploit prediction
EPSS: 0.005 (42.5th percentile), scored .
Very low probability of exploitation in the next 30 days; routine patching cadence is appropriate. 42nd percentile — 42.5% of CVEs in the catalogue have a lower EPSS than this one. How to read EPSS.
EPSS over last 30 days · oldest: 0.005 · newest: 0.005 · change: 0.000
Affected products
- Openclinica Community Edition — versions 3.0, 3.1, 3.2
- Openclinica — versions 3.12.2, 3.13
Weakness classification (CWE)
References
- vuldb.com/ (technical-description, VDB Entry, Third Party Advisory, vdb-entry)
- vuldb.com/ (signature, Permissions Required, permissions-required, VDB Entry)
- vuldb.com/ (VDB Entry, Third Party Advisory, third-party-advisory)
- github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe… (related, Exploit, Third Party Advisory)
- github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe… (Exploit, Third Party Advisory, exploit)
Frequently asked questions
- What is CVE-2025-12921?
- CVE-2025-12921 is a medium-severity vulnerability in Openclinica Community Edition, classified under Improper Neutralization of Special Elements in Output Used by a Downstream Component (Injection). CVSS score: 4.3/10. Published 2025-11-10.
- How severe is CVE-2025-12921?
- Medium severity. CVSS v3 base score is 4.3 out of 10.